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Propofol is known to possess direct antiemetic effects. Propofol antiemetic use for induction and maintenance of anesthesia has been shown to be associated with a lower incidence of postoperative nausea and vomiting (PONV) when compared to any other anesthetic drug or technique.

1996 The Association of Antiemetic effect of propofol administered at the end of surgery in laparoscopic assisted vaginal hysterectomy. Item Preview > Controversy exists regarding the effectiveness of propofol to prevent postoperative nausea and vomiting. This prospective, randomized, single-blinded study was designed to evaluate the antiemetic effectiveness of 0.5 mg/kg propofol when administered intravenously after sevoflurane- compared with desflurane-based anesthesia. Download Citation | The Use of Propofol as an Antiemetic | The widespread use of propofol for general anesthesia led to the realization that propofol has an intrinsic antiemetic property. However 2019-09-14 · Other reports suggest that the antiemetic effect of propofol is due to modulation of the subcortical pathways . Patients who received propofol experienced a significant reduction in nausea and vomiting compared with patients treated with placebo. Postoperative nausea and vomiting (PONV) is still a clinical problem and its incidence is unacceptably high.

During the first postoperative 2 hours, antiemetics were Postoperative nausea and vomiting (PONV) are unpleasant, often underestimated side effects of anaesthesia and surgery, not devoid of medical complications. Prevention with antiemetics is only partially effective. Propofol has been shown recently to possess antiemetic properties in several situations. In this prospective, randomized, controlled trial, we have compared the antiemetic efficacy … 1996-10-01 Antiemetic effect of propofol Anaesthesia is a stressful specialty and if stress-associated conditions are more common in anaesthetists than in other hospital specialists this may be partly due to the lower status and prestige which has historically dogged the profession, especially in comparison to … 1996-10-01 Antiemetic effect of propofol administered at the end of surgery in laparoscopic assisted vaginal hysterectomy Eu-Gene Kim, Hye Jin Park, Hyoseok Kang, Juyoun Choi, and Hyun Jeong Lee Department of Anesthesiology and Pain Medicine, Eulji General Hospital, Eulji University College of … 2014-03-28 Propofol is known to possess direct antiemetic effects. Its use for induction and maintenance of anaesthesia has been shown to be associated with a lower incidence of postoperative nausea and vomiting (PONV) when compared to any other anaesthetic drug or technique. However, its mechanism of action in this context is still not well understood.

Nov 2, 2018 In addition to the sedative or anesthetic effects of propofol, there are Anti- emetic: Propofol can help to prevent or treat nausea and vomiting.

BACKGROUND: Postoperative nausea and vomiting (PONV) commonly occur after general anesthesia, especially in women. There is evidence that the antiemetic effect of propofol is associated with a defined plasma concentration range; mean, 343 ng/mL (10–90% confidence intervals [CI] 200–600 ng/mL).

Propofol is known to possess direct antiemetic effects. Its use for induction and maintenance of anaesthesia has been shown to be associated with a lower incidence of postoperative nausea and vomiting (PONV) when compared to any other anaesthetic drug or technique. However, its mechanism of action in this context is still not well understood.

However, pharmacokinetic data suggest that the use of propofol purely for induction of anaesthesia, But, their effect mechanisms are not fully clarified [8]. Dexamethasone is a glucocorticoid and has been used as an antiemetic drug in patients receiving Abstract. Propofol is known to possess direct antiemetic effects. Its use for induction and maintenance of anaesthesia has been shown to be associated with a propofol reduces the incidence of PONV compared with inhalational anaesthesia ,4–10 especially in women.5–7 This antiemetic effect is limited to the early Nausea and vomiting are distressing side effects of chemotherapy particularly The mechanism of antiemetic action of propofol has not been investigated to Mar 10, 2015 Propofol is believed to be an antiemetic and therefore is usefull to dopamine receptor antagonists) have undesirable adverse effects, such as very few side effects and was not different from place- bo.

Postoperative nausea and vomiting (PONV) are unpleasant, often underestimated side effects of anaesthesia and surgery, not devoid of medical complications. Prevention with antiemetics is only partially effective. Propofol has been shown recently to possess antiemetic properties in several situations. Prevention with antiemetics is only partially effective. Propofol has been shown recently to possess antiemetic properties in several situations. In this prospective, randomized, controlled trial, we have compared the antiemetic efficacy of subhypnotic doses of propofol, with Intralipid as placebo, after thyroidectomy.
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Furthermore, small dose of Antiemetic effect of propofol Antiemetic effect of propofol Borgeat, A. 1996-11-01 00:00:00 W.G. NOTCUTT I read with interest H.F. Seeleyâ s article (Anaesthesia 1996; 51: 571-4) on the causes and outcome of stress amongst anaesthetists. Anaesthesia is a stressful specialty and if stress-associated conditions are more common in anaesthetists Propofol decreased synaptic transmission in the olfactory cortex in an animal study, suggesting a decrease in the release of excitatory amino acids such as glutamate and aspartate, which may be related to its antiemetic activity [ 14 ].

In order to investigate the putative anti-emetic effect of propofol, 53 patients undergoing gynaecological laparoscopy were given a standard anaesthetic including induction with thiopentone. NOTE: The antiemetic effect of propofol is greatest during the infusion with an increased risk of nausea and vomiting after drug administration cessation. NOTE: Prevention of nausea and vomiting appears to be associated with a plasma propofol concentration between 280 and 530 ng/mL. 2020-08-24 · Warning.
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Propofol is known to exert an antiemetic effect even though the exact mechanism is still unclear. One study reported that propofol reduces PONV by blocking the 5-hydroxy-tryptamin-3 receptor of the serotonergic system, 20 , 21 while others reported that inhibition of the chemoreceptor trigger zone and vagal nuclei, which are directly related to nausea and vomiting, is associated with the

1996 Nov;51(11):1073-4. Antiemetic effect of propofol. Borgeat A. Comment on Anaesthesia. 1996 Jun;51(6):554-7. PMID: 8943606 Propofol is known to possess direct antiemetic effects.